Conventional treatments for ankylosing spondylitis

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EXTENDED REPORT Conventional treatments for ankylosing spondylitis

Management of ankylosing spondylitis (AS) is challenged by the progressive nature of the disease. To date, no intervention is available that alters the underlying mechanism of inflammation in AS. Currently available conventional treatments are palliative at best, and often fail to control symptoms in the long term. Current drug treatment may perhaps induce a spurious state of “disease remission...

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Urolithiasis in ankylosing spondylitis: Correlation with Bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis functional index (BASFI) and Bath ankylosing spondylitis metrology index (BASMI)

Background: Increased incidence of renal stone has been reported in ankylosing spondylitis (AS), but unlike some well-known renal involvements, they have not been fully studied. The aim of this study was to investigate the association of AS with urolithiasis and also the relation between urinary stone and severity markers. Methods: One hundred-sixty three AS patients were included in a cross-s...

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ASSOCIATION OF HLA-B27 WITH ANKYLOSING SPONDYLITIS IN ISFAHAN, IRAN

Using a standard microcytotoxicity (NIH) technique of tissue typing, the HLA-B27 antigen was identified in 30 out of 34 patients (HH.2%) with classical ankylosing spondylitis (AS), compared to 6 out of 70 controls (H.6%) (P < 0.005). We also found this antigen in 8 out of 76 (10.5%) patients with non-AS arthritis.

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Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology

The objective of this study was to determine the prevalence and risk factors of low bone mineral density (BMD) in patients with Spondylarthropathies (SpA) at an early stage of disease. In this cross-sectional study, the BMD of lumbar spine and hips was measured in 130 consecutive early SpA patients. The outcome measure BMD was defined as (1) osteoporosis, (2) osteopenia and (3) normal bone dens...

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Genetic breakthrough for ankylosing spondylitis

Ankylosing spondylitis (AS) is a chronic form of arthritis that attacks the spine, causing the vertebrae to fuse, resulting in loss of normal curvature, as well as affecting other joints and organs. New findings concerning the genetic basis of the disease could lead to novel therapies for the condition, which is thought to affect around one in 200 men and one in 500 women, usually developing du...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2002

ISSN: 0003-4967

DOI: 10.1136/ard.61.suppl_3.iii40